Scientists Have Finally Discovered What Happens To Your Skin When You Have Eczema • MetDaan

Scientists Have Finally Discovered What Happens To Your Skin When You Have Eczema

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Having sensitive or dry skin is not an issue, but having to scratch it every five minutes is pretty annoying. It happens so often that people don’t realize that Eczema can be quite painful and unbearable. It causes much pain for some people, but, luckily, more people find their own solution to that. From babies to grownups, eczema is quite common. Worldwide, about 20 percent of children and up to 3 percent of the adult population have some form of eczema. This chronic condition occurs when people often complain of sore, red itchy patches on their skin. But scientists have finally discovered what’s really going on to your skin when you have it.

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Until now, no one is actually sure why this condition happens.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

But there are some things we know about the condition.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

Eczema is an inflammation of the skin with unknown cause. It’s actually the most common form of the skin condition called atopic dermatitis. This is all closely related to asthma or allergic rhinitis as well. Usually, it starts in childhood, but adults also have it. It’s estimated that over 245 million people are the world suffer from eczema.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

Sadly, there is no one cure that helps, although there are several creams and ointments that will relieve the itch.

Although for years now there have been several creams and ointments out there to help relieve the itch which is a symptom of eczema, there’s no cure that will make it go away. Not yet anyway, but we’re now one step closer to making that happen!

However, scientists are now closer than ever before to finding out the processes that occur in a person’s skin when they have eczema. Knowing this could help them how to cure it for good.

Ten years ago, scientists discovered that sufferers of eczema usually have a lack of a gene called filaggrin in their bodies. This was the clue for researchers.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

Filaggrin is a protein that is used by the body to help shape skin cells and creating the skin’s barrier. If you are born with an imbalance of this important protein in their skin, it can result in eczema, or ichthyosis vulgaris, on which the skin doesn’t shed properly. This is when dead skin isn’t shed properly, and can stay on the body. It will eventually look like fish scales.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

Scientists at Newcastle University in England partnered with the dermatologist pharmaceutical company GSK Stiefel. They wanted to figure out the series of proteins and pathways involved that can trigger eczema.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

“We have shown for the first time that loss of the filaggrin protein alone is sufficient to alter key proteins and pathways involved in triggering eczema,” lead researcher Nick Reynolds of Newcastle University says.

The team then created a 3-D model called a Living Skin Equivalent, or LSE for short, in order to search these mechanisms.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

Next, they altered the top layer of the LSE so that the amount of filaggrin it had was too small. This is very similar to people who suffer from eczema. What they found was that when skin is lacking filaggrin, it can alter the molecular model of the skin. So the skin’s cell structure, barrier function, and how the cells can become inflamed and respond to stress isn’t as good as would normally be.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

“Notably, for the first time, we have identified 17 proteins that are significantly differentially expressed after [filaggrin removal] in LSE cultures,” the team wrote.

The team then had to verify their findings and compare them in tests with humans. The results from healthy skin and those who have eczema were both analyzed.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

After the study, they found that many of the proteins were altered in the same way as only those with eczema. It was very similar to the model they created in the lab.

Although they haven’t exactly found a cure for it yet, they’re on the right track.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

This will help scientists develop medications to stop this from happening in the future.

Scientists Have Discovered What Really Happens To Your Skin When You Have Eczema

A mother discovered the perfect cure for her daughter’s eczema, so if you want to help someone, here is her story.

 * This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances.
Source: auntyacid

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